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Cathepsin K inhibitors increase distal femoral bone mineral density in rapidly growing rabbits
BACKGROUND: Selective and reversible inhibitors of human Cathepsin K (CatK), including odanacatib (ODN), have been developed as potential therapeutics for the treatment of osteoporosis. Inhibitors of human CatK show significantly less potency for the rodent enzymes compared with that for the human o...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3878918/ https://ncbi.nlm.nih.gov/pubmed/24321244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-14-344 |
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