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Macropinocytosis is the Major Pathway Responsible for DNA Transfection in CHO cells by a Charge-Reversal Amphiphile
The cellular uptake of a functional charge-reversal amphiphile:DNA lipoplex is described. First, pharmacological inhibitors were applied to block different endocytosis pathways. By examining the resulting transfection activities, it was found that endocytosis was the pathway leading to transfection...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3878857/ https://ncbi.nlm.nih.gov/pubmed/21449536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp100366h |
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