Epigenetic silencing of glutaminase 2 in human liver and colon cancers

BACKGROUND: Glutaminase 2 (Gls2) is a p53 target gene and is known to play an important role in energy metabolism. Gls2 has been reported to be downregulated in human hepatocellular carcinomas (HCC). However, the underlying mechanism responsible for its downregulation is still unclear. Here, we inve...

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Autori principali: Zhang, Jianbin, Wang, Cheng, Chen, Mingquan, Cao, Jianping, Zhong, Ying, Chen, Liting, Shen, Han-Ming, Xia, Dajing
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878668/
https://ncbi.nlm.nih.gov/pubmed/24330717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-601
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