B Epitope Multiplicity and B/T Epitope Orientation Influence Immunogenicity of Foot-and-Mouth Disease Peptide Vaccines

Synthetic peptides incorporating protective B- and T-cell epitopes are candidates for new safer foot-and-mouth disease (FMD) vaccines. We have reported that dendrimeric peptides including four copies of a B-cell epitope (VP1 136 to 154) linked to a T-cell epitope (3A 21 to 35) of FMD virus (FMDV) el...

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Detalhes bibliográficos
Main Authors: Blanco, Esther, Cubillos, Carolina, Moreno, Noelia, Bárcena, Juan, de la Torre, Beatriz G., Andreu, David, Sobrino, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878600/
https://ncbi.nlm.nih.gov/pubmed/24454475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/475960
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