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Complement Protein C3 Binding to Mycobacterium tuberculosis Is Initiated by the Classical Pathway in Human Bronchoalveolar Lavage Fluid

In high concentrations of fresh nonimmune human serum, Mycobacterium tuberculosis activates the alternative pathway of complement and binds C3 protein, resulting in enhanced phagocytosis by complement receptors on human alveolar macrophages. Yet in the lung, the alternative pathway of complement is...

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Pubblicato in:Infect Immun
Autori principali: Ferguson, J. Scott, Weis, Jeremy J., Martin, Jennifer L., Schlesinger, Larry S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2004
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387845/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15102764/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.5.2564-2573.2004
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