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Loss of IP(3) receptor function in neuropeptide secreting neurons leads to obesity in adult Drosophila

BACKGROUND: Intracellular calcium signaling regulates a variety of cellular and physiological processes. The inositol 1,4,5 trisphosphate receptor (IP(3)R) is a ligand gated calcium channel present on the membranes of endoplasmic reticular stores. In previous work we have shown that Drosophila mutan...

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Autores principales: Subramanian, Manivannan, Jayakumar, Siddharth, Richhariya, Shlesha, Hasan, Gaiti
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878400/
https://ncbi.nlm.nih.gov/pubmed/24350669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-14-157
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