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Assessment of single-dose benzodiazepines on insulin secretion, insulin sensitivity and glucose effectiveness in healthy volunteers: a double-blind, placebo-controlled, randomized cross-over trial [ISRCTN08745124]

BACKGROUND: The present study aimed at investigating in healthy volunteers the effects of diazepam and clonazepam on beta-cell function, insulin sensitivity and glucose effectiveness based on the frequently sampled intravenous (0.5 gkg(-1)) glucose tolerance test with minimal-model analysis. METHODS...

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Detalhes bibliográficos
Main Authors: Chevassus, Hugues, Mourand, Isabelle, Molinier, Nathalie, Lacarelle, Bruno, Brun, Jean-Frédéric, Petit, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC387833/
https://ncbi.nlm.nih.gov/pubmed/15102335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6904-4-3
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