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Single molecule fluorescence experiments determine protein folding transition path times

The transition path is the tiny fraction of an equilibrium molecular trajectory when a transition occurs by crossing the free-energy barrier between two states. It is a single-molecule property that contains all the mechanistic information on how a process occurs. As a step toward observing transiti...

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Detalhes bibliográficos
Main Authors: Chung, Hoi Sung, McHale, Kevin, Louis, John M., Eaton, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878298/
https://ncbi.nlm.nih.gov/pubmed/22363011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1215768
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