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Leptin modulates electrophysiological characteristics and isoproterenol-induced arrhythmogenesis in atrial myocytes

BACKGROUND: Obesity is an important risk factor for atrial fibrillation (AF). Leptin is an important adipokine. However, it is not clear whether leptin directly modulates the electrophysiological characteristics of atrial myocytes. RESULTS: Whole cell patch clamp and indo-1 fluorescence were used to...

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Bibliographic Details
Main Authors: Lin, Yung-Kuo, Chen, Yao-Chang, Huang, Jen-Hung, Lin, Yenn-Jiang, Huang, Shiang-Suo, Chen, Shih-Ann, Chen, Yi-Jen
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878176/
https://ncbi.nlm.nih.gov/pubmed/24354396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-20-94
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