Leptin modulates electrophysiological characteristics and isoproterenol-induced arrhythmogenesis in atrial myocytes

BACKGROUND: Obesity is an important risk factor for atrial fibrillation (AF). Leptin is an important adipokine. However, it is not clear whether leptin directly modulates the electrophysiological characteristics of atrial myocytes. RESULTS: Whole cell patch clamp and indo-1 fluorescence were used to...

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Detalhes bibliográficos
Principais autores: Lin, Yung-Kuo, Chen, Yao-Chang, Huang, Jen-Hung, Lin, Yenn-Jiang, Huang, Shiang-Suo, Chen, Shih-Ann, Chen, Yi-Jen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878176/
https://ncbi.nlm.nih.gov/pubmed/24354396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-20-94
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