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Leptin modulates electrophysiological characteristics and isoproterenol-induced arrhythmogenesis in atrial myocytes

BACKGROUND: Obesity is an important risk factor for atrial fibrillation (AF). Leptin is an important adipokine. However, it is not clear whether leptin directly modulates the electrophysiological characteristics of atrial myocytes. RESULTS: Whole cell patch clamp and indo-1 fluorescence were used to...

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Détails bibliographiques
Auteurs principaux: Lin, Yung-Kuo, Chen, Yao-Chang, Huang, Jen-Hung, Lin, Yenn-Jiang, Huang, Shiang-Suo, Chen, Shih-Ann, Chen, Yi-Jen
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878176/
https://ncbi.nlm.nih.gov/pubmed/24354396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-20-94
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