Local production of CCL3, CCL11, and IFN-γ correlates with disease severity in murine parainfluenza virus infection

BACKGROUND: Using a murine model of parainfluenza virus infection (mPIV1 or Sendai virus; SeV), we compared the inflammatory responses to lethal and sub-lethal infections in inbred DBA/2 mice. METHODS: Mice were intranasally inoculated with either 1.6×10(3) or 1.6×10(5) infectious units (IU) of SeV...

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Autori principali: Suryadevara, Manika, Bonville, Cynthia A, Rosenberg, Helene F, Domachowske, Joseph B
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878101/
https://ncbi.nlm.nih.gov/pubmed/24359540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-357
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