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The Ewing’s Sarcoma Fusion Protein, EWS-FLI, Binds Runx2 and Blocks Osteoblast Differentiation
Ewing’s sarcomas are highly aggressive round cell tumors of bone and soft tissues that afflict children and young adults. The majority of these tumors harbor the t(11;22) translocation and express the fusion protein EWS-FLI. Modern molecular profiling experiments indicate that Ewing’s tumors origina...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3877924/ https://ncbi.nlm.nih.gov/pubmed/20665663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22782 |
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