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Multiple small RNA pathways regulate the silencing of repeated and foreign genes in C. elegans

Gene segments from other organisms, such as viruses, are detected as foreign and targeted for silencing by RNAi pathways. A deep-sequencing map of the small RNA response to repeated transgenes introduced to Caenorhabditis elegans revealed that specific segments are targeted by siRNAs. Silencing of t...

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Sonraí Bibleagrafaíochta
Main Authors: Fischer, Sylvia E.J., Pan, Qi, Breen, Peter C., Qi, Yan, Shi, Zhen, Zhang, Chi, Ruvkun, Gary
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877757/
https://ncbi.nlm.nih.gov/pubmed/24352423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.233254.113
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