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Integrating protein-protein interaction networks with phenotypes reveals signs of interactions
A major objective of systems biology is to organize molecular interactions as networks and to characterize information-flow within networks. We describe a computational framework to integrate protein-protein interaction (PPI) networks and genetic screens to predict the “signs” of interactions (i.e....
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3877743/ https://ncbi.nlm.nih.gov/pubmed/24240319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2733 |
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