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Novel SCN3A Variants Associated with Focal Epilepsy in Children

Voltage-gated sodium (Na(V)) channels are essential for initiating and propagating action potentials in the brain. More than 800 mutations in genes encoding neuronal Na(V) channels including SCN1A and SCN2A have been associated with human epilepsy. Only one epilepsy-associated mutation has been iden...

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Bibliografiske detaljer
Main Authors: Vanoye, Carlos G., Gurnett, Christina A., Holland, Katherine D., George, Alfred L., Kearney, Jennifer A.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877720/
https://ncbi.nlm.nih.gov/pubmed/24157691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.10.015
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