Axonal and synaptic failure suppress the transfer of firing rate oscillations, synchrony and information during high frequency deep brain stimulation

High frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a widely used treatment for Parkinson's disease, but its effects on neural activity in basal ganglia circuits are not fully understood. DBS increases the excitation of STN efferents yet decouples STN spiking pattern...

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Hlavní autoři: Rosenbaum, Robert, Zimnik, Andrew, Zheng, Fang, Turner, Robert S., Alzheimer, Christian, Doiron, Brent, Rubin, Jonathan E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877705/
https://ncbi.nlm.nih.gov/pubmed/24051279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.09.006
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