Evidence that Collaboration between HIF-1α and Notch-1 Promotes Neuronal Cell Death in Ischemic Stroke

Recent findings suggest that Notch-1 signaling contributes to neuronal death in ischemic stroke, but the underlying mechanisms are unknown. Hypoxia inducible factor-1α (HIF-1α), a global regulator of cellular responses to hypoxia, can interact with Notch and modulate its signaling during hypoxic str...

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Detalhes bibliográficos
Main Authors: Cheng, Yi-Lin, Park, Jong-Sung, Manzanero, Silvia, Choi, Yuri, Baik, Sang-Ha, Okun, Eitan, Gelderblom, Mathias, Fann, David Yang-Wei, Magnus, Tim, Launikonis, Bradley S., Mattson, Mark P., Sobey, Christopher G., Jo, Dong-Gyu, Arumugam, Thiruma V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877697/
https://ncbi.nlm.nih.gov/pubmed/24141018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.10.009
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