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MAP3K1: Genomic Alterations in Cancer and Function in Promoting Cell Survival or Apoptosis
MAP3K1 is a member of the mitogen-activated protein kinase kinase kinase (MAP3K) family of serine/threonine kinases. MAP3K1 regulates JNK activation and is unique among human kinases in that it also encodes an E3 ligase domain that ubiquitylates c-Jun and ERK1/2. Full length MAP3K1 regulates cell mi...
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| Main Authors: | , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
SAGE Publications
2013
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3877667/ https://ncbi.nlm.nih.gov/pubmed/24386504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601913513950 |
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