A candidate anti-HIV reservoir compound, auranofin, exerts a selective ‘anti-memory' effect by exploiting the baseline oxidative status of lymphocytes

Central memory (T(CM)) and transitional memory (T(TM)) CD4(+) T cells are known to be the major cellular reservoirs for HIV, as these cells can harbor a transcriptionally silent form of viral DNA that is not targeted by either the immune system or current antiretroviral drug regimens. In the present...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chirullo, B, Sgarbanti, R, Limongi, D, Shytaj, I L, Alvarez, D, Das, B, Boe, A, DaFonseca, S, Chomont, N, Liotta, L, III Petricoin, E, Norelli, S, Pelosi, E, Garaci, E, Savarino, A, Palamara, A T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877546/
https://ncbi.nlm.nih.gov/pubmed/24309931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.473
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados