Direct modulation of the outer mitochondrial membrane channel, voltage-dependent anion channel 1 (VDAC1) by cannabidiol: a novel mechanism for cannabinoid-induced cell death

Cannabidiol (CBD) is a non-psychoactive plant cannabinoid that inhibits cell proliferation and induces cell death of cancer cells and activated immune cells. It is not an agonist of the classical CB1/CB2 cannabinoid receptors and the mechanism by which it functions is unknown. Here, we studied the e...

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Main Authors: Rimmerman, N, Ben-Hail, D, Porat, Z, Juknat, A, Kozela, E, Daniels, M P, Connelly, P S, Leishman, E, Bradshaw, H B, Shoshan-Barmatz, V, Vogel, Z
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877544/
https://ncbi.nlm.nih.gov/pubmed/24309936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.471
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