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Effect of insulin on excitatory synaptic transmission onto dopamine neurons of the ventral tegmental area in a mouse model of hyperinsulinemia

Obesity has drastically increased over the last few decades. Obesity is associated with elevated insulin levels, which can gain access to the brain, including into dopamine neurons of the ventral tegmental area (VTA), a brain region critical for mediating reward-seeking behavior. Synaptic plasticity...

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Autori principali: Liu, S, Labouèbe, G, Karunakaran, S, Clee, S M, Borgland, S L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877429/
https://ncbi.nlm.nih.gov/pubmed/24336291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nutd.2013.38
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