Syndecan-1 (CD138) Modulates Triple-Negative Breast Cancer Stem Cell Properties via Regulation of LRP-6 and IL-6-Mediated STAT3 Signaling

Syndecan-1 (CD138), a heparan sulfate proteoglycan, acts as a coreceptor for growth factors and chemokines and is a molecular marker associated with epithelial-mesenchymal transition during development and carcinogenesis. Resistance of Syndecan-1-deficient mice to experimentally-induced tumorigenesi...

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Detalhes bibliográficos
Main Authors: Ibrahim, Sherif A., Hassan, Hebatallah, Vilardo, Laura, Kumar, Sampath Katakam, Kumar, Archana Vijaya, Kelsch, Reinhard, Schneider, Cornelia, Kiesel, Ludwig, Eich, Hans Theodor, Zucchi, Ileana, Reinbold, Rolland, Greve, Burkhard, Götte, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877388/
https://ncbi.nlm.nih.gov/pubmed/24392029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085737
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