Adapter Protein SH2-Bβ Undergoes Nucleocytoplasmic Shuttling: Implications for Nerve Growth Factor Induction of Neuronal Differentiation

The adapter protein SH2-B has been shown to bind to activated nerve growth factor (NGF) receptor TrkA and has been implicated in NGF-induced neuronal differentiation and the survival of sympathetic neurons. However, the mechanism by which SH2-B enhances and maintains neurite outgrowth is unclear. We...

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Autores principales: Chen, Linyi, Carter-Su, Christin
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Nucleocytoplasmic Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC387738/
https://ncbi.nlm.nih.gov/pubmed/15082760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.9.3633-3647.2004
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