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The MEK/ERK Pathway Promotes NOTCH Signalling in Pancreatic Cancer Cells
Activation of the NOTCH receptors relies on their intracellular proteolysis by the gamma-secretase complex. This cleavage liberates the NOTCH intracellular domain (NIC) thereby allowing the translocation of NIC towards the nucleus to assemble into a transcriptional platform. Little information is av...
Gorde:
| Egile Nagusiak: | , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Public Library of Science
2013
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3877363/ https://ncbi.nlm.nih.gov/pubmed/24392017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085502 |
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