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The Conserved Lid Tryptophan, W211, Potentiates Thermostability and Thermoactivity in Bacterial Thermoalkalophilic Lipases

We hypothesize that aggregation of thermoalkalophilic lipases could be a thermostability mechanism. The conserved tryptophans (W211, W234) in the lid are of particular interest owing to their previous involvements in aggregation and thermostability mechanisms in many other proteins. The thermoalkalo...

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Detalhes bibliográficos
Main Authors: Timucin, Emel, Sezerman, O Ugur
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877348/
https://ncbi.nlm.nih.gov/pubmed/24391996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085186
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