MIDDAS-M: Motif-Independent De Novo Detection of Secondary Metabolite Gene Clusters through the Integration of Genome Sequencing and Transcriptome Data

Many bioactive natural products are produced as “secondary metabolites” by plants, bacteria, and fungi. During the middle of the 20th century, several secondary metabolites from fungi revolutionized the pharmaceutical industry, for example, penicillin, lovastatin, and cyclosporine. They are generall...

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Detalhes bibliográficos
Main Authors: Umemura, Myco, Koike, Hideaki, Nagano, Nozomi, Ishii, Tomoko, Kawano, Jin, Yamane, Noriko, Kozone, Ikuko, Horimoto, Katsuhisa, Shin-ya, Kazuo, Asai, Kiyoshi, Yu, Jiujiang, Bennett, Joan W., Machida, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877130/
https://ncbi.nlm.nih.gov/pubmed/24391870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084028
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