MIDDAS-M: Motif-Independent De Novo Detection of Secondary Metabolite Gene Clusters through the Integration of Genome Sequencing and Transcriptome Data

Many bioactive natural products are produced as “secondary metabolites” by plants, bacteria, and fungi. During the middle of the 20th century, several secondary metabolites from fungi revolutionized the pharmaceutical industry, for example, penicillin, lovastatin, and cyclosporine. They are generall...

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Bibliographische Detailangaben
Hauptverfasser: Umemura, Myco, Koike, Hideaki, Nagano, Nozomi, Ishii, Tomoko, Kawano, Jin, Yamane, Noriko, Kozone, Ikuko, Horimoto, Katsuhisa, Shin-ya, Kazuo, Asai, Kiyoshi, Yu, Jiujiang, Bennett, Joan W., Machida, Masayuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877130/
https://ncbi.nlm.nih.gov/pubmed/24391870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084028
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