A Novel SP1/SP3 Dependent Intronic Enhancer Governing Transcription of the UCP3 Gene in Brown Adipocytes

Uncoupling protein (UCP) 3 is a mitochondrial inner membrane protein implicated in lipid handling and metabolism of reactive oxygen species. Its transcription is mainly regulated by peroxisome proliferator-activated receptors (PPAR), a family of nuclear hormone receptors. Employing bandshift assays,...

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Detalhes bibliográficos
Main Authors: Hoffmann, Christoph, Zimmermann, Anika, Hinney, Anke, Volckmar, Anna-Lena, Jarrett, Harry W., Fromme, Tobias, Klingenspor, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877035/
https://ncbi.nlm.nih.gov/pubmed/24391766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083426
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