Targeted Expression of Suicide Gene by Tissue-Specific Promoter and MicroRNA Regulation for Cancer Gene Therapy

In order to realise the full potential of cancer suicide gene therapy that allows the precise expression of suicide gene in cancer cells, we used a tissue specific Epithelial cell adhesion molecule (EpCAM) promoter (EGP-2) that directs transgene Herpes simplex virus–thymidine kinase (HSV-TK) express...

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Detalhes bibliográficos
Main Authors: Danda, Ravikanth, Krishnan, Gopinath, Ganapathy, Kalaivani, Krishnan, Uma Maheswari, Vikas, Khetan, Elchuri, Sailaja, Chatterjee, Nivedita, Krishnakumar, Subramanian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877029/
https://ncbi.nlm.nih.gov/pubmed/24391761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083398
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