Proteomic Profiling of Exosomes Leads to the Identification of Novel Biomarkers for Prostate Cancer

BACKGROUND: Current markers for prostate cancer, such as PSA lack specificity. Therefore, novel biomarkers are needed. Unfortunately, the complexity of body fluids often hampers biomarker discovery. An attractive alternative approach is the isolation of small vesicles, i.e. exosomes, ∼100 nm, which...

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Detalhes bibliográficos
Main Authors: Duijvesz, Diederick, Burnum-Johnson, Kristin E., Gritsenko, Marina A., Hoogland, A. Marije, Vredenbregt-van den Berg, Mirella S., Willemsen, Rob, Luider, Theo, Paša-Tolić, Ljiljana, Jenster, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876995/
https://ncbi.nlm.nih.gov/pubmed/24391718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082589
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