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Segregation of Family A G Protein–Coupled Receptor Protomers in the Plasma Membrane

G protein–coupled receptors (GPCRs) transduce many important physiological signals and are targets for a large fraction of therapeutic drugs. Members of the largest family of GPCRs (family A) are thought to self-associate as dimers and higher-order oligomers, although the significance of such quater...

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Hlavní autoři: Gavalas, Anthony, Lan, Tien-Hung, Liu, Qiuju, Corrêa, Ivan R., Javitch, Jonathan A., Lambert, Nevin A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876820/
https://ncbi.nlm.nih.gov/pubmed/23778362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.086868
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