CCAAT/Enhancer Binding Protein α Binds to the Epstein-Barr Virus (EBV) ZTA Protein through Oligomeric Interactions and Contributes to Cooperative Transcriptional Activation of the ZTA Promoter through Direct Binding to the ZII and ZIIIB Motifs during Induction of the EBV Lytic Cycle

The Epstein-Barr virus (EBV)-encoded ZTA protein interacts strongly with and stabilizes the cellular CCAAT/enhancer binding protein α (C/EBPα), leading to the induction of p21-mediated G(1) cell cycle arrest. Despite the strong interaction between these two basic leucine zipper (bZIP) family protein...

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Detalhes bibliográficos
Main Authors: Wu, Frederick Y., Wang, Shizhen Emily, Chen, Honglin, Wang, Ling, Hayward, S. Diane, Hayward, Gary S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC387681/
https://ncbi.nlm.nih.gov/pubmed/15078966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.9.4847-4865.2004
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