JC Virus Induces Nonapoptotic Cell Death of Human Central Nervous System Progenitor Cell-Derived Astrocytes

JC virus (JCV), a human neurotropic polyomavirus, demonstrates a selective glial cell tropism that causes cell death through lytic infection. Whether these cells die via apoptosis or necrosis following infection with JCV remains unclear. To investigate the mechanism of virus-induced cell death, we u...

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Pubblicato in:	J Virol
Autori principali:	Seth, Pankaj, Diaz, Frank, Tao-Cheng, Jung-Hwa, Major, Eugene O.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2004
Soggetti:	Virus-Cell Interactions
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387680/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15078969/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.9.4884-4891.2004
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