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Using State Variables to Model the Response of Tumour Cells to Radiation and Heat: A Novel Multi-Hit-Repair Approach

In order to overcome the limitations of the linear-quadratic model and include synergistic effects of heat and radiation, a novel radiobiological model is proposed. The model is based on a chain of cell populations which are characterized by the number of radiation induced damages (hits). Cells can...

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Detalhes bibliográficos
Main Authors: Scheidegger, Stephan, Fuchs, Hans U., Zaugg, Kathrin, Bodis, Stephan, Füchslin, Rudolf M.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876778/
https://ncbi.nlm.nih.gov/pubmed/24396395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/587543
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