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In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains.

Emerging evidence suggests that an amplifiable protease cascade consisting of multiple aspartate specific cysteine proteases (ASCPs) is responsible for the apoptotic changes observed in mammalian cells undergoing programmed cell death. Here we describe the cloning of two novel ASCPs from human Jurka...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Fernandes-Alnemri, T, Armstrong, R C, Krebs, J, Srinivasula, S M, Wang, L, Bullrich, F, Fritz, L C, Trapani, J A, Tomaselli, K J, Litwack, G, Alnemri, E S
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1996
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38767/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8755496/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.15.7464
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