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Defects in the N-Linked Oligosaccharide Biosynthetic Pathway in a Trypanosoma brucei Glycosylation Mutant

Concanavalin A (ConA) kills the procyclic (insect) form of Trypanosoma brucei by binding to its major surface glycoprotein, procyclin. We previously isolated a mutant cell line, ConA 1-1, that is less agglutinated and more resistant to ConA killing than are wild-type (WT) cells. Subsequently we foun...

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Udgivet i:Eukaryot Cell
Principais autores: Acosta-Serrano, Alvaro, O'Rear, Jessica, Quellhorst, George, Lee, Soo Hee, Hwa, Kuo-Yuan, Krag, Sharon S., Englund, Paul T.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387663/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15075256/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/EC.3.2.255-263.2004
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