Synthesis of a Novel Siliconized Analog of Clofibrate (Silafibrate) and Comparison of their Anti-inflammatory Activities

Fibrates, as hypolipidemic drugs known as agonists of peroxisome proliferator-activated receptors, diminish inflammatory responses. Studies have shown that incorporation of a silicon atom into a drug structure improves its pharmacological potency, modifies its selectivity toward a given target, or c...

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Detalhes bibliográficos
Main Authors: Ziaee, Mojtaba, Samini, Morteza, Bolourtchian, Mohammad, Ghaffarzadeh, Mohammad, Ahmadi, Maryam, Egbal, Mohammad Ali, Khorrami, Arash, Andalib, Sina, Maleki-Dizaji, Nasrin, Garjani, Alireza
Formato: Artigo
Idioma:Inglês
Publicado em: Shaheed Beheshti University of Medical Sciences 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876562/
https://ncbi.nlm.nih.gov/pubmed/25317189
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