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Design, Synthesis and Pharmacological Evaluation of Novel 2-[2-(2-Chlorophenoxy) phenyl]-1,3,4-oxadiazole Derivatives as Benzodiazepine Receptor Agonists

New derivatives of 2-[2-(2-Chlorophenoxy)phenyl]-1,3,4-oxadiazole as candidates for agonistic effect on benzodiazepine receptors were synthesized. Conformational analysis and superimposition of energy minima conformers of the novel compounds on estazolam, a known benzodiazepine agonist, revealed tha...

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Библиографические подробности
Главные авторы: Faizi, Mehrdad, Sheikhha, Majid, Ahangar, Nematollah, Tabatabaei Ghomi, Hamed, Shafaghi, Bijan, Shafiee, Abbas, Tabatabai, Seyyed Abbas
Формат: Artigo
Язык:Inglês
Опубликовано: Shaheed Beheshti University of Medical Sciences 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876560/
https://ncbi.nlm.nih.gov/pubmed/25317188
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