Mitochondrial Histone-Like DNA-Binding Proteins Are Essential for Normal Cell Growth and Mitochondrial Function in Crithidia fasciculata

The Crithidia fasciculata KAP2 and KAP3 proteins are closely related kinetoplast-specific histone-like DNA-binding proteins. The KAP2 and KAP3 genes are 46% identical and are arranged in tandem on the chromosomal DNA. Disruption of both alleles of either gene alone shows no detectable phenotype. How...

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Bibliographic Details
Main Authors: Avliyakulov, Nuraly K., Lukeš, Julius, Ray, Dan S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC387644/
https://ncbi.nlm.nih.gov/pubmed/15075280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.3.2.518-526.2004
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