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Estimation of treatment effect under nonproportional hazards and conditionally independent censoring

In clinical trials with time-to-event outcomes, it is common to estimate the marginal hazard ratio from the proportional hazards model, even when the proportional hazards assumption is not valid. This is unavoidable from the perspective that the estimator must be specified a priori if probability st...

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Autores principales: Boyd, Adam P., Kittelson, John M., Gillen, Daniel L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876422/
https://ncbi.nlm.nih.gov/pubmed/22763957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.5440
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