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Transformation of Benign Barrett’s Epithelium by Repeated Acid and Bile Exposure over 65 Weeks: A novel In-Vitro Model
The mechanism by which gastroesophageal reflux promotes metaplasia→dysplasia→ carcinoma is unknown. The aim of the study is to determine if repeated exposure to acid and bile confers a tumorigenic phenotype in a telomerase (hTERT)-immortalized benign Barrett’s cell line, BAR-T. BAR-T cells were expo...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3876418/ https://ncbi.nlm.nih.gov/pubmed/20309934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25343 |
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