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Antagonism of SAMHD1 is actively maintained in natural infections of simian immunodeficiency virus
Restriction factors are effectors of the innate immune response to viral pathogens that inhibit viral replication by operating as molecular barriers to steps of the viral life cycle. The restriction factor SAMHD1 blocks lentiviral reverse transcription in myeloid cells and resting CD4+ T cells. Many...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3876209/ https://ncbi.nlm.nih.gov/pubmed/24324150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316839110 |
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