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SYBR Green-Based Real-Time Quantitative PCR Assay for Detection of West Nile Virus Circumvents False-Negative Results Due to Strain Variability

Real-time quantitative PCR is used routinely for the high-throughput diagnosis of viral pathogens, such as West Nile virus (WNV). Rapidly evolving RNA viruses present a challenge for diagnosis because they accumulate mutations that may render them undetectable. To explore the effect of sequence vari...

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Bibliografiske detaljer
Main Authors: Papin, James F., Vahrson, Wolfgang, Dittmer, Dirk P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC387603/
https://ncbi.nlm.nih.gov/pubmed/15070997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.42.4.1511-1518.2004
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