Bone marrow adipocytes promote tumor growth in bone via FABP4-dependent mechanisms

Incidence of skeletal metastases and death from prostate cancer greatly increases with age and obesity, conditions which increase marrow adiposity. Bone marrow adipocytes are metabolically active components of bone metastatic niche that modulate the function of neighboring cells; yet the mechanisms...

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Detalhes bibliográficos
Main Authors: Herroon, Mackenzie K., Rajagurubandara, Erandi, Hardaway, Aimalie L., Powell, Katelyn, Turchick, Audrey, Feldmann, Daniel, Podgorski, Izabela
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875773/
https://ncbi.nlm.nih.gov/pubmed/24240026
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