Hyperlipidemia-Associated Renal Damage Decreases Klotho Expression in Kidneys from ApoE Knockout Mice

BACKGROUND: Klotho is a renal protein with anti-aging properties that is downregulated in conditions related to kidney injury. Hyperlipidemia accelerates the progression of renal damage, but the mechanisms of the deleterious effects of hyperlipidemia remain unclear. METHODS: We evaluated whether hyp...

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Main Authors: Sastre, Cristina, Rubio-Navarro, Alfonso, Buendía, Irene, Gómez-Guerrero, Carmen, Blanco, Julia, Mas, Sebastian, Egido, Jesús, Blanco-Colio, Luis Miguel, Ortiz, Alberto, Moreno, Juan Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875485/
https://ncbi.nlm.nih.gov/pubmed/24386260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083713
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