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MicroRNA Drop in the Bloodstream and MicroRNA Boost in the Tumour Caused by Treatment with Ribonuclease A Leads to an Attenuation of Tumour Malignancy

Novel data showing an important role of microRNAs in mediating tumour progression opened a new field of possible molecular targets for cytotoxic ribonucleases. Recently, antitumour and antimetastatic activities of pancreatic ribonuclease A were demonstrated and here genome-wide profiles of microRNAs...

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Bibliografiske detaljer
Main Authors: Mironova, Nadezhda, Patutina, Olga, Brenner, Evgenyi, Kurilshikov, Alexander, Vlassov, Valentin, Zenkova, Marina
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875445/
https://ncbi.nlm.nih.gov/pubmed/24386211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083482
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