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Effect of Polyplex Morphology on Cellular Uptake, Intracellular Trafficking, and Transgene Expression

Nanoparticle morphology has been shown to affect cellular uptake, but there are few studies investigating the impact of particle shape on biologic drug delivery. Recently, our group synthesized a series of N-(2-hydroxypropyl) methacrylamide (HPMA)-oligolysine brush polymers for nucleic acid delivery...

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Bibliografiska uppgifter
Huvudupphovsmän: Shi, Julie, Choi, Jennifer L., Chou, Brian, Johnson, Russell N., Schellinger, Joan G., Pun, Suzie H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874816/
https://ncbi.nlm.nih.gov/pubmed/24195594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn403069n
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