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Effect of Polyplex Morphology on Cellular Uptake, Intracellular Trafficking, and Transgene Expression

Nanoparticle morphology has been shown to affect cellular uptake, but there are few studies investigating the impact of particle shape on biologic drug delivery. Recently, our group synthesized a series of N-(2-hydroxypropyl) methacrylamide (HPMA)-oligolysine brush polymers for nucleic acid delivery...

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Autori principali: Shi, Julie, Choi, Jennifer L., Chou, Brian, Johnson, Russell N., Schellinger, Joan G., Pun, Suzie H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874816/
https://ncbi.nlm.nih.gov/pubmed/24195594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn403069n
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