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Effect of Polyplex Morphology on Cellular Uptake, Intracellular Trafficking, and Transgene Expression

Nanoparticle morphology has been shown to affect cellular uptake, but there are few studies investigating the impact of particle shape on biologic drug delivery. Recently, our group synthesized a series of N-(2-hydroxypropyl) methacrylamide (HPMA)-oligolysine brush polymers for nucleic acid delivery...

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Detalhes bibliográficos
Main Authors: Shi, Julie, Choi, Jennifer L., Chou, Brian, Johnson, Russell N., Schellinger, Joan G., Pun, Suzie H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874816/
https://ncbi.nlm.nih.gov/pubmed/24195594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn403069n
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