GagPol-specific CD4(+) T-cells increase the antibody response to Env by intrastructural help

BACKGROUND: Immunization of rhesus macaques against Gag of SIV resulted in a more rapid appearance of Env antibodies after infection with SIV or SHIV challenge viruses although the vaccines lacked an Env component. We therefore explored whether T helper cells specific for internal HIV proteins could...

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Détails bibliographiques
Auteurs principaux: Nabi, Ghulam, Genannt Bonsmann, Michael Storcksdieck, Tenbusch, Matthias, Gardt, Oliver, Barouch, Dan H, Temchura, Vladimir, Überla, Klaus
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874777/
https://ncbi.nlm.nih.gov/pubmed/24156704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-117
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