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Cytostatic versus cytocidal profiling of quinoline drug combinations via modified fixed-ratio isobologram analysis

BACKGROUND: Drug combination therapy is the frontline of malaria treatment. There is an ever-accelerating need for new, efficacious combination therapies active against drug resistant malaria. Proven drugs already in the treatment pipeline, such as the quinolines, are important components of current...

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Main Authors: Gorka, Alexander P, Jacobs, Lauren M, Roepe, Paul D
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874740/
https://ncbi.nlm.nih.gov/pubmed/24044530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-12-332
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