K(V)7 channels are involved in hypoxia-induced vasodilatation of porcine coronary arteries

BACKGROUND AND PURPOSE: Hypoxia causes vasodilatation of coronary arteries, but the underlying mechanisms are poorly understood. We hypothesized that hypoxia reduces intracellular Ca(2+) concentration ([Ca(2+)](i)) by opening of K channels and release of H(2)S. EXPERIMENTAL APPROACH: Porcine coronar...

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Autors principals: Hedegaard, E R, Nielsen, B D, Kun, A, Hughes, A D, Krøigaard, C, Mogensen, S, Matchkov, V V, Fröbert, O, Simonsen, U
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2014
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874697/
https://ncbi.nlm.nih.gov/pubmed/24111896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12424
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