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Putting an ‘End’ to HIV mRNAs: capping and polyadenylation as potential therapeutic targets

Like most cellular mRNAs, the 5′ end of HIV mRNAs is capped and the 3′ end matured by the process of polyadenylation. There are, however, several rather unique and interesting aspects of these post-transcriptional processes on HIV transcripts. Capping of the highly structured 5′ end of HIV mRNAs is...

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Detalhes bibliográficos
Autor principal: Wilusz, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874655/
https://ncbi.nlm.nih.gov/pubmed/24330569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-6405-10-31
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