Pdx1 and controlled culture conditions induced differentiation of human amniotic fluid-derived stem cells to insulin-producing clusters

This study investigated the differentiation of human amniotic fluid-derived stem cells (hAFSCs) into insulin-producing clusters in vitro. Adenovirally-delivered mouse Pdx1 (Ad-Pdx1) induced human Pdx1 expression in hAFSCs and enhanced the coordinated expression of downstream b-cell markers. When Ad-...

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Detalhes bibliográficos
Main Authors: Chun, So Young, Mack, David L., Moorefield, Emily, Oh, Se Heang, Kwon, Tae Gyun, Pettenati, Mark J., Yoo, James J., Atala, Anthony, Soker, Shay
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874429/
https://ncbi.nlm.nih.gov/pubmed/23147868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/term.1631
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